Rino Cella
Rino Cella
affiliation: University of Pavia
research area(s): Molecular Biology, Developmental Biology
Course: Biomolecular Sciences and Biotechnology
University/Istitution: Istituto Universitario di Studi Superiori, Pavia
· 1968 University of Pavia (Italy), Biology Degree
· 1968-1970 University of Pavia (Italy), Specialization course.
· 1972-1974 Dalhousie University, Halifax (Canada), Post-doc
· 1974-1975 University of Leicester (UK), Post-doc
The research activity of the last decade has been mainly devoted to the functional characterization of some plant cell cycle regulators and DNA polymerases. In the case of E2F transcription factors, their role during cell proliferation and development was investigated.
Recently, the scientific activity has partly shifted towards applied aspects with particular reference to the production of recombinant proteins of commercial interest using transgenic and transplatomic tobacco plants (molecular farming and molecular pharming).
The common feature of both lines is the use of molecular genetics tools.
Di An N, Sozzani R, Blanchet S, Domenichini S, Reuzeau C, Cella R, Catherine Bergounioux C and Raynaud C (2009) The Arabidopsis MCM2 gene is essential to embryo development and its over-expression alters root meristem function. New Phytologist 184: 311-322

Sozzani R, Maggio C, Giordo R, Umana E, Ascencio-Ibanez JT, Hanley-Bowdoin L, Bergounioux Cella R and Albani D (2010) The E2F/DEL2 factor is a component of a regulatory network controlling cell proliferation and development in Arabidopsis. Plant Mol Biol 72: 381-395

Amoroso A, Concia L, Maggio C, Raynaud C, Bergounioux C, Crespan E, Cella R, Maga G (2011) Oxidative DNA damage bypass in Arabidopsis thaliana requires DNA polymerase λ and proliferating cell nuclear antigen 2. Plant Cell, 23 :806-22.
Leelavathi S, Bhardwaj A, Kumar S, Dass A, Pathak R, Pandey SS, Tripathy BC, Padmalatha KV, Dhandapani G, Kanakachari M, Kumar PA, Cella R, Siva Reddy V (2011) Genome-wide transcrptome and proteome analyses of tobacco psaA and psbA mutants. Plant Mol Biol, 76: 407-23
Project Title:
Production of recombinant proteins in transgenic tobacco plants
The project aims at the production of several recombinant enzymes of commercial interest.