Antonella Ragnini-Wilson
Antonella Ragnini-Wilson
affiliation: Università di Roma Tor Vergata
research area(s): Cell Biology, Genetics And Genomics
Course: Cell and Molecular Biology
University/Istitution: Università di Roma Tor Vergata
Teaching experience
•University courses:
2002-present: Methodologies in Biochemistry and Molecular Biology (University of Tor Vergata Rome) Italy for the University courses “Laurea triennale” in Human Biology and Cellular and Molecular biology.

1994-2009: List of courses at University of Vienna, at Max Perutz laboratories Dr.Bohrgasse 9 Vienna (Austria )
Sommersemester 2009 300051 PS Dynamic Biochemistry - for Students of the Masterprogramm Molecular Biology Studienprogrammleitung Biologie (0.25Std)
300380 SE Reading and Discussing Publications in Biochemistry .Studienprogrammleitung Biologie (0.25Std)
Sommersemester 2000 809093 UE Experimentelle Genetik III (Molekulargenetik)
Wintersemester 1999/00 809141 UE Experimentelle Genetik III (Molekularbiologie)
Sommersemester 1999 809093 UE Experimentelle Genetik III (Molekulargenetik)
Wintersemester 1998/99 809141 UE Experimentelle Genetik III (Molekularbiologie)
Sommersemester 1998 809093 UE Experimentielle Genetik III (Molekulargenetik)
Wintersemester 1997/98 809141 UE Experimentelle Genetik III (Molekularbiologie)
Sommersemester 1997 809093 UE Experimentielle Genetik III (Molekulargenetik)
Wintersemester 1996/97 809141 UE Experimentelle Genetik III (Molekularbiologie)
Sommersemester 1996 809093 UE Experimentielle Genetik III (Molekulargenetik)
Wintersemester 1995/96 809141 UE Experimentelle Genetik III (Molekularbiologie)
809416 UE Experimentelle Genetik/Mikrobiologie III (Molekulargenetik)
Sommersemester 1995-809802 UE Exp. Genetik/Mikrobiologie III (DNA/RNA Technol. u. Klonierg.)
Wintersemester 1994/95-809135 UE Experimentelle Genetik/Mikrobiologie III (DNA/RNA Technol. u. Klonierung)
• Supervisor of diploma and Ph.D. theses at the University of Vienna (1991-2002) and at the University of Rome “Tor Vergata” (2002-present), Open University Cambridge (Uk) 2006-present). Member of the Docent committee for the PhD program in Cellular and Molecular Biology University of “Tor Vergata”
Teaching Languages: English, Italian
see web site:
Conserved molecular mechanisms underlying homeostasis of the Golgi complex.
Wilson C, Ragnini-Wilson A.Int J Cell Biol. 2010;2010:758230. Epub 2010 Oct 3.
PMID:20976261[PubMed - in process] Free PMC Article

A yeast-based genomic strategy highlights the cell protein networks altered by FTase inhibitor peptidomimetics.
Porcu G, Wilson C, Di Giandomenico D, Ragnini-Wilson A.
Mol Cancer. 2010 Jul 23;9:197.
PMID:20653956[PubMed - indexed for MEDLINE] Free PMC Article

.N-lobe dynamics of myosin light chain dictates its mode of interaction with myosin V IQ1.Amata I, Gallo M, Pennestri M, Paci M, Ragnini-Wilson A, Cicero DO.
Biochemistry. 2008 Nov 25;47(47):12332-45.PMID:18975975[PubMed - indexed for MEDLINE]

.Ypt32p and Mlc1p bind within the vesicle binding region of the class V myosin Myo2p globular tail domain.Casavola EC, Catucci A, Bielli P, Di Pentima A, Porcu G, Pennestri M, Cicero DO, Ragnini-Wilson A.Mol Microbiol. 2008 Mar;67(5):1051-66. Epub 2008 Jan 23.
PMID:18221262[PubMed - indexed for MEDLINE]

Structural basis for the interaction of the myosin light chain Mlc1p with the myosin V Myo2p IQ motifs.Pennestri M, Melino S, Contessa GM, Casavola EC, Paci M, Ragnini-Wilson A, Cicero DO.J Biol Chem. 2007 Jan 5;282(1):667-79. Epub 2006 Oct 29.
PMID:17074768[PubMed - indexed for MEDLINE] Free Article

GTP drives myosin light chain 1 interaction with the class V myosin Myo2 IQ motifs via a Sec2 RabGEF-mediated pathway.
Bielli P, Casavola EC, Biroccio A, Urbani A, Ragnini-Wilson A.
Mol Microbiol. 2006 Mar;59(5):1576-90.
PMID:16468996[PubMed - indexed for MEDLINE]

Large pleiomorphic traffic intermediates in the secretory pathway.
Luini A, Ragnini-Wilson A, Polishchuck RS, De Matteis MA.
Curr Opin Cell Biol. 2005 Aug;17(4):353-61. Review.
PMID:15993575[PubMed - indexed for MEDLINE]

Assignment of the 1H, 13C and 15N resonances of Mlc1p from Saccharomices cerevisiae.Melino S, Pennestri M, Santoprete A, Bielli P, Paci M, Ragnini-Wilson A, Cicero DO.J Biomol NMR. 2005 Apr;31(4):367-8. No abstract available.
PMID:15929007[PubMed - indexed for MEDLINE]

Previous significative publications
Mlc1p promotes septum closure during cytokinesis via the IQ motifs of the vesicle motor Myo2p.Wagner W, Bielli P, Wacha S, Ragnini-Wilson A.
EMBO J. 2002 Dec 2;21(23):6397-408.

■Bialek-Wyrzykowska U., Bauer B.E., Wagner W., Kohlwein S.D., Schweyen R.J., Ragnini A.
Low levels of Ypt protein prenylation cause vesicle polarization defects and thermosensitive growth that can be suppressed by genes involved in cell wall maintenance.
Mol Microbiol., 35: 1295-1311 (2000)
PubMed Full text
■Miaczynska M., Lorenzetti S., Bialek U., Benito-Moreno R.M., Schweyen R.J., Ragnini A.
The yeast Rab escort protein binds intracellular membranes in vivo and in vitro.
J. Biol. Chem., 272: 16972-16977 (1997).
PubMed Full text
■Bauer B.E., Lorenzetti S., Miaczynska M., Bui D.M., Schweyen R.J., Ragnini A.
Amino- and carboxy-terminal domains of the yeast Rab escort protein are both required for binding of Ypt small G proteins.
Mol. Biol. Cell, 7: 1521-1533 (1996).
PubMed Full text
■Waldherr M., Ragnini A., Schweyer R.J., Boguski M.S.
MRS6--yeast homologue of the choroideraemia gene.
Nat. Genet., 3: 193-194 (1993).
PubMed Full text
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