Marina De Bernard
Marina De Bernard
affiliation: Università di Padova
research area(s): Immunity And Infection, Cell Biology
Course: Biosciences and Biotechnologies
University/Istitution: Università di Padova

1993: Degree in Biological Sciences, cum laude, at the University of Padua, Italy
1994-1997: PhD in Molecular and Cellular Pathology, University of Padua, Italy, awarded June 8th, 1998.
1997-1999: research Fellowship at the Dept. of Biomedical Sciences, University of Padua, Italy
2000: Visiting scientist EMBL, laboratory of Dr. M. Zerial, Heidelberg, Germany
1999-2002: Research Fellowship at the Dept. of Biomedical Sciences, University of Padua, Italy
2002-2010 Assistant Professor at the Faculty of Sciences, Dept. of Biology, University of Padua, Italy
2010-present: Associate Professor of General Pathology at the Faculty of Sciences, Dept. of Biology, University of Padua, Italy
2005-present: Group leader of the “Host pathogen Interaction” research unit at the Department of Biology of the University of Padua and at the Venetian Institute of Molecular Medicine (VIMM) in Padua.
My reasearch is focussedon the characterization of bacterial products endowed with immune modulatory properties with the aim of disclosing novel molecular and cellular mechanisms of immune response to H. pylori and other bacterial pathogens giving chronic infections in humans. I am interested also on the practical side, i.e. the development of novel therapeutic strategies.

Benagiano M, Munari F, Ciervo A, Amedei A, Paccani SR, Mancini F, Ferrari M,
Della Bella C, Ulivi C, D'Elios S, Baldari CT, Prisco D, de Bernard M, D'Elios
MM. (2012) Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis. Proc Natl Acad Sci U S A.109:1222-1227.

Chiumiento L, Del Prete G, Codolo G, De Bernard M, Amedei A, Della Bella C,
Piazza M, D'Elios S, Caponi L, D'Elios MM, Bruschi F. (2011) Stimulation of TH1 response by Helicobacter pylori neutrophil activating protein decreases the protective role of IgE and eosinophils in experimental trichinellosis. Int J Immunopathol Pharmacol. 24:895-903.

Codolo G, Fassan M, Munari F, Volpe A, Bassi P, Rugge M, Pagano F, D'Elios MM,
de Bernard M. (2012) HP-NAP inhibits the growth of bladder cancer in mice by activating a cytotoxic Th1 response. Cancer Immunol Immunother. 61:31-40.

Babolin C, Amedei A, Ozolins D, Zilevica A, D'Elios MM, de Bernard M. (2011) TpF1 from Treponema pallidum activates inflammasome and promotes the development of regulatory T cells. J Immunol. 187:1377-1384.

Munari F, Lonardi S, Cassatella MA, Doglioni C, Cangi MG, Amedei A, Facchetti
F, Eishi Y, Rugge M, Fassan M, de Bernard M, D'Elios MM, Vermi W. (2011)
Tumor-associated macrophages as major source of APRIL in gastric MALT lymphoma. Blood. 117:6612-6616.

Fassan M, Volinia S, Palatini J, Pizzi M, Baffa R, De Bernard M, Battaglia G,
Parente P, Croce CM, Zaninotto G, Ancona E, Rugge M. (2011) MicroRNA expression profiling in human Barrett's carcinogenesis. Int J Cancer. 129:1661-1670.

Codolo G, Papinutto E, Polenghi A, D'Elios MM, Zanotti G, de Bernard M. (2010)
Structure and immunomodulatory property relationship in NapA of Borrelia
burgdorferi. Biochim Biophys Acta. 1804:2191-2197.

Calore F, Genisset C, Casellato A, Rossato M, Codolo G, Esposti MD, Scorrano
L, de Bernard M. (2010) Endosome-mitochondria juxtaposition during apoptosis induced by H. pylori VacA. Cell Death Differ. 17:1707-1716.

D'Elios MM, de Bernard M. (2010) To treat or not to treat Helicobacter pylori to benefit asthma patients. Expert Rev Respir Med. 4:147-150.

Cappon A, Babolin C, Segat D, Cancian L, Amedei A, Calzetti F, Cassatella MA,
D'Elios MM, de Bernard M. (2010) Helicobacter pylori-derived neutrophil-activating protein increases the lifespan of monocytes and neutrophils. Cell Microbiol. 12:754-764.

Amedei A, Codolo G, Del Prete G, de Bernard M, D'Elios MM. (2010) The effect of Helicobacter pylori on asthma and allergy. J Asthma Allergy. 3:139-147.

de Bernard M, D'Elios MM. (2010) The immune modulating activity of the Helicobacter pylori HP-NAP: Friend or foe? Toxicon. 56:1186-1192.

D'Elios MM, Codolo G, de Bernard M. (2009) Reply to letter by Nardelli and Schell commenting on the pathogenesis of Lyme arthritis. Arthritis Rheum. 60:2205.

Debellis L, Diana A, Arcidiacono D, Fiorotto R, Portincasa P, Altomare DF,
Spirlì C, de Bernard M. (2009) The Vibrio cholerae cytolysin promotes chloride secretion from intact human intestinal mucosa. PLoS One.4:e5074.

Salata C, Curtarello M, Calistri A, Sartori E, Sette P, de Bernard M, Parolin
C, Palù G. (2009) vOX2 glycoprotein of human herpesvirus 8 modulates human primary macrophages activity. J Cell Physiol. 219:698-706.

D'Elios MM, Codolo G, Amedei A, Mazzi P, Berton G, Zanotti G, Del Prete G, de
Bernard M. (2009) Helicobacter pylori, asthma and allergy. FEMS Immunol Med Microbiol. 56:1-8.

Codolo G, Amedei A, Steere AC, Papinutto E, Cappon A, Polenghi A, Benagiano
M, Paccani SR, Sambri V, Del Prete G, Baldari CT, Zanotti G, Montecucco C,
D'Elios MM, de Bernard M. (2008) Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis. Arthritis Rheum. 58:3609-3617.

Del Prete G, Chiumiento L, Amedei A, Piazza M, D'Elios MM, Codolo G, de
Bernard M, Masetti M, Bruschi F. (2008) Immunosuppression of TH2 responses in
Trichinella spiralis infection by Helicobacter pylori neutrophil-activating
protein. J Allergy Clin Immunol. 122:908-913.e5.

Codolo G, Mazzi P, Amedei A, Del Prete G, Berton G, D'Elios MM, de Bernard M. (2008) The neutrophil-activating protein of Helicobacter pylori down-modulates Th2 inflammation in ovalbumin-induced allergic asthma. Cell Microbiol. 10:2355-2363.

Farinati F, Cardin R, Bortolami M, Nitti D, Basso D, de Bernard M, Cassaro M,
Sergio A, Rugge M. (2008) Oxidative DNA damage in gastric cancer: CagA status and OGG1 gene polymorphism. Int J Cancer. 123:51-55.

Arcidiacono D, Odom S, Frossi B, Rivera J, Paccani SR, Baldari CT, Pucillo C,
Montecucco C, de Bernard M. (2008) The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine production. Cell Microbiol. 10:899-907.

No projects are available to students for the current accademic year.