Mario Quarantelli
Mario Quarantelli
affiliation: Università di Napoli Federico II
research area(s): Neuroscience
Course: Neurosciences
University/Istitution: Università di Napoli Federico II
Work Address:
Edificio 10, Via Pansini 5
80131 Napoli
Date and place of Birth: 5 April 1965, Ercolano (NA), ITALY
Profile - Educational and Scientific Profile
•1 January 2007 to date: Senior Researcher, Biostructure and Bioimaging Institute of Naples (formerly Center for Nuclear Medicine) of the National Research Council (Dir. B. Alfano)
•1 September 1998 to 31 December 2006: Researcher, Biostructure and Bioimaging Institute of Naples (formerly Center for Nuclear Medicine) of the National Research Council (Dir. B. Alfano)
•May 2001 to date: Faculty member of the Neuroscience PhD program, University "Federico II" of Naples (Coordinator Prof. L. Annunziato)
•December 2000 to date: Consultant radiologist, University Hospital "Federico II" of Naples (Dir. Prof. M. Salvatore)
•January 2007 to December 2008: Faculty member, Orthoptic Studies and Ophthalmological Assistance Degree Course, University "Federico II" of Naples (Director Prof. A. Magli)
•January 2004 to December 2006: Faculty member, Diagnostic Imaging and Radiotherapy Techniques Degree Course, University "Federico II" of Naples (Director Prof. M. Salvatore)
•1 June-31 August 1998: Neuroradiologist at the "Nuovo Pellegrini" Hospital in Naples. (Chief Dr. R. Apolito)
•Specialization in Radiology cum Laude: 1 November 1998, Second University of Naples
•Authorization to medical protection for radiation safety purposes (D.P.R. 12.12.1972, n.1150): 4 June 1996
•Special Volunteer from February 10, 1992 to February 9, 1993 and Visiting Fellow from February 10, 1993 - February 9, 1994 at the Neuroimaging Branch, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD.
•Specialization in Nuclear Medicine cum Laude: 28 October 1993, First University of Naples
•Medical habilitation: 1989 (Order of the Physicians membership number 24491)
•Medical degree cum Laude: 23 October 1989, Catholic University of Sacred Heart of Rome
Ad-hoc reviewer for several international journals including JNNP - Journal of Neurology, Neurosurgery & Psychiatry, Journal of Cerebral Blood Flow and Metabolism, NeuroImage, Brain, European Journal of Nuclear Medicine and Molecular Imaging, Neurological Sciences, Journal of Cellular Physiology, Journal of Neuroimaging, Quarterly Journal of Nuclear Medicine and Molecular Imaging, BioMED Central Nuclear Medicine, Psychiatry Research: Neuroimaging, Latin American Applied Research, Computer Methods and Programs in Biomedicine
Evaluator for several International Research Funding Institutions, including European Commission (COST and Marie Curie Fellowships Actions under the 6th and 7th Framework Programmes), European Science Foundation, INTAS
Main research interests of Dr. Quarantelli are in the field of integrated analysis of functional (PET, functional MRI, MRSI) and structural (conventional MRI, Diffusion Tensor) neuroimaging data, both in terms of methodological developments and application in the study of neuro-physiopathology.
Following these research lines, Dr. Quarantelli has developed the main module of a software package (PVELab) for the integrated analysis of PET and MRI data, widely used worldwide in the research centers where both PET and MRI are available. The paper describing PVELab (J Nucl Med 2004 45:192-201 ) has been cited to date in more than 120 publications.
Dr Quarantelli has published the first quantitative analysis of the relationship between white matter lesion load and gray matter atrophy in multiple sclerosis (NeuroImage 2003 18:360–366).

Current research activities include:
•Development of new algorithms in the fields of brain MRI segmentation for the study of macro-structural alterations of brain tissues
•Development of new algorithms for the integrated analysis of multimodality neuroimaging data
•Study of macro- and micro-structural alterations of brain tissues in neurodegenerative and neuroinflammatory diseases
•Study of structural and functional connectivity alterations in neurodegenerative and neuroinflammatory diseases
•Clinical research on the diagnostic role of MRI in prenatal neuroimaging
•Study of the relationship between inflammatory and neurodegenerative aspects in animal models of Multiple Sclerosis, Amyotrophic Lateral Sclerosis, and Stroke
1.Grossi D, Soricelli A, Ponari M, Salvatore E, Quarantelli M, Prinster A, Trojano L. Structural connectivity in a single case of progressive prosopagnosia: the role of the right inferior longitudinal fasciculus. Cortex (in press)
2.Paladini D, Quarantelli M, Sglavo G, Pastore G, Cavallaro A, D'Armiento, Salvatore M, Nappi C. The role of MRI in the clinical management of foetuses with central nervous system abnormalities in a tertiary referral center. Ultrasound Obstet Gynecol (in press)
3.Ristori G, Romano S, Cannoni S, Visconti A, Tinelli E, Mendozzi L, Cecconi P, Lanzillo R, Quarantelli M, Buttinelli C, Gasperini C, Frontoni M, Coarelli G, Caputo D, Brescia Morra V, Vanacore N, Pozzilli C, Salvetti M. Effects of Bacille Calmette-Guerin after the first demyelinating event in the CNS. Neurology (in press)
4.Quarantelli M, Salvatore E, Giorgio SMdA, Filla A, Cervo A, Russo CV, Cocozza S, Massarelli M, Brunetti A, De Michele G. Default-mode network changes in Huntington's Disease: an integrated MRI study of functional connectivity and morphometry. PLoS ONE 2013;8(8):e72159 doi:10.1371/journal.pone.0072159
5.Jacobs AH, Tavitian B, and the INMiND consortium. Noninvasive molecular imaging of neuroinflammation.Journal of Cerebral Blood Flow & Metabolism 2012;32,1393-1415
Project Title:
Study of the relationship between the alterations of structural connectivity, functional connectivity and brain tissue volumes in Multiple Sclerosis

Project Title:
Relationship between functional connectivity and glucose metabolism in Alzheimer’s disease