Gianni Biolo
Gianni Biolo
affiliation: Università di Trieste - Dip Clinico di Scienze mediche
research area(s): Experimental Medicine
Course: Molecular Biomedicine
University/Istitution: Università di Trieste
Director Clinical Molecular Medicine, Trieste University Hospital.
Associate Professor of Internal Medicine, Department of Medical Science, University of Trieste;
ADDRESS: Università di Trieste, Clinica Medica - Ospedale di Cattinara, Strada di Fiume 447, 34149 Trieste, Italy.
Ph: +39 040 399 4532; +39 338 7318408 (mobile); Fax: +39 040 399 4593; Email:
BIOGRAPHICAL DATA: date of birth: October 15th, 1959; place of birth: Venezia, Italy; citizenship: Italian
EDUCATION: (1986) M.D. degree Univ. of Padova; (1989) Specialization degree in Endocrinology, Univ. of Padova; (1994) Ph.D. degree in Clinical Pathophysiology, Univ. of Milan; (2000) Specialization degree in Internal Medicine, Univ. of Trieste.
GRADUATE CLINICAL AND RESEARCH TRAINING: 1986-1991: Residency, Division of Diabetes and Metabolic Diseases, Univ. of Padova; 1991-1992: Postoctoral Fellow, University of Texas Medical Branch, Galveston, Texas.
ACADEMIC APPOINTMENTS: 1993-1994: Assistant Professor of Internal Medicine, University of Texas Medical Branch, Galveston, Texas; 1995-2002: Assistant Professor of Internal Medicine, University of Trieste; 2002-present: Associate Professor of Internal Medicine, University of Trieste.
SCIENTIFIC APPOINTMENTS: Scientific Committee Chairman of the European Society of Metabolism and Clinical Nutrition (ESPEN) (2004-2008); Associate Editor of Clinical Nutrition (2006-2010); Executive Committee member of the Italian Society of Artificial nutrition and Metabolism (SINPE) (2005-2008); Member of the Working Group on Nutrition and Metabolism of the European Society of Intensive Care Medicine (ESICM) (from 1997). Member of the Working Group on Space Nutrition of the European Space Agency (ESA) (from 2006).
112 publications quoted in . Impact Factor, total: 506; average: 4.7. Total citations: 3132, ( >300/year from 2008).
98 invited lectures at national and international meetings [2011 ESPEN Cuthbertson Lecture (European Society of Clinical Nutrition and Metabolism; 2007 Royal Society of Medicine. London, UK; 1992 J.W. McLaughlin Post-Doctoral Fellowship (University of Texas, Galveston, Texas, USA); 1991 H.M. Vars Research Award (American Society of Parenteral and Enteral Nutrition)]
"" 2002: Italian Space Agency (Protein nutrition during experimental bed rest in volunteers)
"" 2002-2003: European Space Agency-DLR Cologne Germany (Energy restriction during experimental bed rest in volunteers)
"" 2005-2006: European, American, Canadian Space Agencies-CNES Toulouse France (Cardiovascular risk factors and metabolic syndrome in women during 2-month bed rest).
"" 2004-2005: Nestlé Clinical Research - Lausanne Switzerland (Optimization of protein nutrition, whey vs. casein, in bedridden patients).
"" 2003: Novartis Clinical Nutrition-CRO Aviano (muscle metabolism in cancer patients).
"" 2004-2007: Novartis Clinical Nutrition-CRO Aviano (impact of glucose control on muscle metabolism).
"" 2005-2007: Ministero della Salute " Istituto Mario Negri Bergamo (Progetto Margherita 3) (Glucose control in critically ill patients)
"" 2006-2008: Italian Space Agency (Protein nutrition in aging)
"" 2006-2008: Italian Space Agency (Protein nutrition in space flight)
"" 2007-20010: MIUR (Italian research Council. (Physical activity and nutrition to prevent cancer cachexia.)
"" 2008-2011: European Space Agency " Alkalinizing diet to prevent oxidative stress and muscle atrophy in microgravity.
"" 2011-2013: European Commission POR-FESR Friuli-Venezia Giulia. Prevention of cardiometabolic risk in diabetes.
"" 2012-2014: European Commission FP7th. Metabolic effects of hypoxia.
"" 2012-1024: European Commission INTERREG Italy-Slovenia. Physical activity in ageing.
1. Donatelli F, Corbella D, Di Nicola M, Carli F, Lorini L, Fumagalli R, Biolo G. Preoperative Insulin Resistance and the Impact of Feeding on Postoperative Protein Balance: A Stable Isotope Study. J Clin Endocrinol Metab. 2011 Aug 31. (I.F. 6.5)
2. High plasma RBP4 is associated with systemic inflammation independently of low RBP4 adipose expression and is normalized by transplantation in non-obese, non-diabetic patients with chronic kidney disease. Barazzoni R, Zanetti M, Semolic A, Pirulli A, Cattin MR, Biolo G, Bosutti A, Panzetta G, Bernardi A, Guarnieri G. Clin Endocrinol (Oxf). 2011 Jan 21. (I.F. 3.2)
3. Agostini F, Dalla Libera L, Rittweger J, Mazzucco S, Jurdana M, Mekjavic IB, Pišot R, Gorza L, Narici M, Biolo G. Effects of inactivity on human muscle glutathione synthesis by a double-tracer and single-biopsy approach. J Physiol. 2010 Dec 15;588(Pt 24):5089-104. (I.F. 4.8)
4. Kozàkovà M, Malshi E, Morizzo C, Pedri S, Santini F, Biolo G, Pagani M, Palombo C. Impact of prolonged cardiac unloading on left ventricular mass and longitudinal myocardial performance: an experimental bed rest study in humans. J Hypertens. 2010 Sep 14. (I.F. 5.0)
5. Mazzucco S, Agostini F, Biolo G. Inactivity-mediated insulin resistance is associated with upregulated pro-inflammatory fatty acids in human cell membranes. Clin Nutr. 2010 Jun;29(3):386-90. (I.F. 3.3)
6. Mazzucco S, Agostini F, Mangogna A, Cattin L, Biolo G. Prolonged inactivity up-regulates cholesteryl ester transfer protein independently of body fat changes in humans. J Clin Endocrinol Metab. 2010 May;95(5):2508-12. (I.F. 6.5)
7. Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C. ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr. 2009 Aug;28(4):387-400. (I.F. 3.3)
8. Dalla Libera L, Ravara B, Gobbo V, Tarricone E, Vitadello M, Biolo G, Vescovo G, Gorza L. A transient antioxidant stress response accompanies the onset of disuse atrophy in human skeletal muscle. J Appl Physiol. 2009 Aug;107(2):549-57.
9. Trudel G, Payne M, Mädler B, Ramachandran N, Lecompte M, Wade C, Biolo G, Blanc S, Hughson R, Bear L, Uhthoff HK. Bone marrow fat accumulation after 60 days of bed rest persisted 1 year after activities were resumed along with hemopoietic stimulation: the Women International Space Simulation for Exploration study. J Appl Physiol. 2009 Aug;107(2):540-8. (I.F. 3.7)
10. Rittweger J, Simunic B, Bilancio G, De Santo NG, Cirillo M, Biolo G, Pisot R, Eiken O, Mekjavic IB, Narici M. Bone loss in the lower leg during 35 days of bed rest is predominantly from the cortical compartment. Bone. 2009 Apr;44(4):612-8. (I.F. 4.1)
11. Antonione R, Caliandro E, Zorat F, Guarnieri G, Heer M, Biolo G. Whey protein ingestion enhances postprandial anabolism during short-term bed rest in young men. J Nutr. 2008 Nov;138(11):2212-6. (I.F. 4.1)
12. Biolo G, Agostini F, Simunic B, Sturma M, Torelli L, Preiser JC, Deby-Dupont G, Magni P, Strollo F, diPrampero P, Guarnieri G, Mekjavic IB, Pišot R, Narici MV. Positive energy balance is associated to accelerated muscle atrophy and increased erythrocyte glutathione turnover during 5 wk of bed rest. Am J Clin Nutr. 2008 Oct;88(4):950-8. (I.F. 6.3)
13. Agostini F, Heer M, Guarnieri G, Biolo G. Physical inactivity decreases whole body glutamine turnover independently from changes in proteolysis. J Physiol. 2008 Oct 1;586(Pt 19):4775-81. (I.F. 4.8)
14. Biolo G, De Cicco M, Lorenzon S, Dal Mas V, Fantin D, Paroni R, Barazzoni R, Zanetti M, Iapichino G, Guarnieri G. Treating hyperglycemia improves skeletal muscle protein metabolism in cancer patients after major surgery. Crit Care Med. 2008 Jun;36(6):1768-75. (I.F. 6.4)
15. Bosutti A, Malaponte G, Zanetti M, Castellino P, Heer M, Guarnieri G, Biolo G. Calorie restriction modulates inactivity-induced changes in the inflammatory markers C-reactive protein and pentraxin-3. J Clin Endocrinol Metab. 2008 Aug;93(8):3226-9. (I.F. 6.5)
16. Biolo G, Stulle M, Bianco F, Mengozzi G, Barazzoni R, Vasile A, Panzetta G, Guarnieri G. Insulin action on glucose and protein metabolism during L-carnitine supplementation in maintenance haemodialysis patients. Nephrol Dial Transplant. 2008 Mar;23(3):991-7. (I.F. 3.3)
17. Biolo G, Ciocchi B, Stulle M, Bosutti A, Barazzoni R, Zanetti M, Antonione R, Lebenstedt M, Platen P, Heer M, Guarnieri G. Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest. Am J Clin Nutr. 2007 Aug;86(2):366-72.
18. Dorfman TA, Levine BD, Tillery T, Peshock RM, Hastings JL, Schneider SM, Macias BR, Biolo G, Hargens AR. Cardiac atrophy in women following bed rest. J Appl Physiol. 2007 Jul;103(1):8-16.
No projects are available to students for the current accademic year.