Elena Salvatore
Elena Salvatore
website: www.unina.it
affiliation: Università di Napoli Federico II
research area(s): Neuroscience
  • Neurosciences
  • Molecular Pathology and Pathophysiology
  • Computational Biology and Bioinformatics
University/Istitution: Università di Napoli Federico II
Born in Napoli (IT) on April 10, 1975
Author of 50 papers published on international journals (with other 7 publications in partnership with Euro-HD network)
Main fields of research are neuroimaging, clinical and molecular aspects of Movement Disorders and Dementia.
Impact Factor: 250,989
H-index: 12
Current position
- Assistant professor of Neurology at the University of Naples Federico II, since 01/06/2005
- Since 2004 member of the European Huntington Disease Network (EuroHD)
- Since 2002 member of the American Academy Association of Neurology (AAN)

- Since 2001 member of the Italian Society of Neurology (SIN)
- Board certification in Radiology on March 20, 2012 with 50/50, at the University of Naples Federico II
- PhD in Neurosciences on February 15, 2008, at the same University
- Board certification in Neurology on October 25, 2004, cum laude, at the same University
- Medical degree "cum laude" at the University of Naples Federico II on July 20, 1999.
Clinical Training/Research Experience:
- GCP training on February 2013, certified by ClinTec
- Coinvestigator in the European study WP5 P001 “Identification of biomarkers sensitive to disease progression in patients with Mild Cognitive Impairment: a clinical study (PharmaCog)”, for the partner p33 SDN-Naples, IT
- Visiting student at the Laboratory of Neurogenetic (Prof. Nicolas Wood, Institute of Neurology, University College, London, UK) in 1998
- Visiting student at the Laboratory of Cell Regulation (Prof. Leonard D. Kohn, National Institutes of Diabetes and Digestive and Kidney Disease, National Institutes of Health, Bethesda, USA) in 1996, thanks to “Leonardo Di Capua”
- Attended the Department of Neurological Science (Prof Alessandro Filla) as student , since 1998
- Student at the Laboratory of General Pathology (Prof. Silvestro Formisano, Department of Cellular and Molecular Biology and Pathology “L. Califano”, University Federico II, Naples, IT) from 1994 to1996
The main research interests are the use of structural and functional neuroimaging methods in combination with clinical and molecular aspects of the main movement disorders (syndromes coreiche , parkinsonism , cerebellar ataxia and paraparesis), to search for a possible biomarker for early diagnosis, monitoring of disease , and for a better understanding of the mechanisms underlying the physiopathogenetic individual diseases. Another field of interest is the role of neuroimaging in dementia and multiple sclerosis.
In particular:
a) clinical and neuropsychological assessment of patients, according to specific scales, post-processing analysis of magnetic resonance images (MRI) of the brain, statistical analysis and discussion of the results of clinical studies of structural neuroimaging, by Voxel based Morphometry (VBM) - RM - neuroimaging microstructural by Diffusion Weighted Imaging MRI, molecular neuroimaging, ioflupano by SPECT, the tracer for the activity of the presynaptic dopamine trasportore by SPECT with ECD for the study of cerebral perfusion, by PET with fluorodeoxyglucose (FDG) for the study of glucose metabolism. These studies were carried out partly in collaboration with other national centers funded by PRIN funds, in part, have been carried out in collaboration with other European networks of centers on the study of Spinocerebellar ataxias (SCA-Euro)and innovation in the Diagnosis of Molecular Imaging (DIMI)
b)the design and enrollment of patients in neuroendocrine studies of possible correlations between clinical, hormonal and Neuroimaging in Huntington's disease, and the creation of an archive of clinical data and video as part of a clinical trial - genetic diagnosis of possible alternatives of " syndromes Coreiche not Huntington "
She is also a member of the European network on Huntington's disease , Euro -HD and as such she is busy in recruitment of patients and entering the details of the observational study REGISTRY, and has collaborated on lines of good clinical practice Italian for Huntington's disease.
- Regarding Multiple Sclerosis is occupied :
a) enrollment and assessment of patients for morphometric studies with VBM -MRI brain and evaluation studies of the association with the Cerebro - Spinal Venous Insufficiency (CCSVI), and the addition of patient clinical data for studies on genetic polymorphisms.
- With regard to dementias was responsible:
a) enrollment , clinical and neuropsychological assessment of patients with cognitive deficits for a correlation study , in the study Italian National Alzheimer's Disease Initiative ( ADNI ) and of the European study PharmaCog, with parameters MRI (atrophy of hippocampus, tractography, functional MRI), FDG -PET and EEG
Babiloni C, Del Percio C, Lizio R, Marzano N, Francesco Infarinato, Soricelli A, Salvatore E, Ferri R, Bonforte C, Tedeschi G, Montella P, Baglieri A, Rodriguez G, Famà F, Nobili F, Vernieri F, Ursini F, Mundi C, Frisoni GB, Rossini PM. (2013)Cortical sources of resting state electroencephalographic alpha rhythms deteriorate across time in subjects with amnesic mild cognitive impairment.
Roberta Lanzillo, Marcello Mancini, Raffaele Liuzzi, Orlando Di Donato, Elena Salvatore, Valentina Maglio, Giovanni Vacca, Luca Amato, Gennaro D¿Anna, Arturo Brunetti, Vincenzo Brescia Morra 2013 Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon
Quarantelli M, Salvatore E, Giorgio SM, Filla A, Cervo A, Russo CV, Cocozza S, Massarelli M, Brunetti A, De Michele G.Default-Mode Network Changes in Huntington's Disease: An Integrated MRI Study of Functional Connectivity and Morphometry.
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