Ornella Semino
Ornella Semino
e-mail:
affiliation: Università di Pavia
research area(s): Genetics And Genomics, Molecular Biology
Course: Genetics, Molecular and Cellular Biology
University/Istitution: Università di Pavia
Academic Position:
Associate Professor of Genetics
Department of Biology and Biotecnology "L. Spallanzani", University of Pavia (Italy).
Tel. (office) +39 0382-985543
Tel. (lab) +39 0382-985544
Fax +39 0382-528496
e-mail: ornella.semino@unipv.it

Education:
1993: "Specializzazione" with honor in Applied Genetics, University of Pavia.
1984: "Laurea" with honor in Biological Sciences, University of Pavia.

Professional Experience:
Since 2011: Associate Professor of Genetics, Department of Biology and Biotecnology "L. Spallanzani", University of Pavia (Italy).
2005-2010: Associate Professor of Genetics, Department of Genetics and Microbiology "A. Buzzati-Traverso", University of Pavia.
Since 2010: Scientific Board Member of the Interdepartmental Centre of Gender Studies, University of Pavia.
Since 2011: Faculty Member of the PhD Program in Genetics, Molecular and Cellular Biology, University of Pavia
2007-2010: Faculty Member of the PhD Program in Genetic and Biomolecular Science, University of Pavia.
2005-2006: Faculty Member of the PhD Program in Molecular Biopathology, University of Calabria, Cosenza.
1993-2004: Research Assistant, Department of Genetics and Microbiology, University of Pavia.
1985-1993: Fellows at the Department of Genetics and Microbiology "A. Buzzati-Traverso", University of Pavia.

Abroad Experience:
2001 (March-April): Associate Researcher, Department of Genetics, Stanford University, Stanford, California.
1999 (July-October): Associate Researcher, Department of Genetics, Stanford University, Stanford, California.
1995 (August): Visiting Researcher, Department of Genetics, University of Leicester, Leicester, UK.
1987 (August): Visiting Researcher, Department of Genetics, Karlovy University, Prague, Czechoslovakia.

Educational Activities:
" Professor of Genetics for students in Biological Sciences (2005-present), in Science and Technology for the Environment and Nature (2007-present).
" Assistant Professor for Genetics (Natural Sciences), Genetics I and Genetics II, Human Genetics and Experimental Biology (Biological Sciences) (1990-2005).
" Board member of the College of teachers of: the PhD in Genetics, Molecular and Cellular Biology, University of Pavia (2007-present); the PhD in Molecular Biopatology, University of Calabria, CS (2005-07); the School of Specialization in "Applied Genetics", University of Pavia, Italy (2005).
" Supervisor of many experimental theses (Degrees in Biological Sciences and Biotechnology; Specialization in Applied Genetics and of Ph.D. in Genetics, Molecular and Cellular Biology.
" Member of various final examination committees (2011/12 - 2008/09 -2007/08: PhD in Biopathology Molecular University of Calabria, Cosenza; December 2007: PhD of Alexandra Rose, University of Madeira, Portugal; 2005/06: PhD in Genetics, Molecular and Cellular Biology, University of Pavia;2004/05: School of Specialization in Applied Genetics, University of Pavia).

Additional information:
- Member of the Italian Genetics Association (AGI).
- Referee for several journals including: Science, American Journal of Human Genetics, European Journal of Human Genetics, Annals of Human Genetics, Current Anthropology, and Croatian Medical Journal, PLos ONE.
- Referee for the South Africa's National Research Foundation.
The primary research interest consists in the understanding of the origin, evolution and patterns of diffusion of human populations through the study of the genetic variation. The research activity, started with the analysis in modern human populations of the maternally transmitted mitochondrial DNA, has continued with the study of the holoandric transmitted Y-chromosome specific and bi-parental inherited markers. Recently, the analysis of human dispersion models associated to the diffusion of the agriculture contributed to extend her interest also to the study of genetic variability in some animal species which, after the domestication, clearly reflects, at least in part, the history of human movements.
Her research activity is documented by 79 publications in extenso (75 articles on International Journals and 4 on books).
Selected Articles in Referred Journals (July 2012-2009)
• Grugni V, Battaglia V, Hooshiar Kashani B, Parolo S, Al-Zahery N, Achilli A, Olivieri A, Gandini F, Houshmand M, Hossein Sanati M, Torroni A, Semino O. Ancient migratory events in the Middle East: new clues from the Y-chromosome variation of modern Iranians. PLos ONE, in press.
• Bonfiglio S, De Gaetano A, Tesfaye K, Grugni V, Semino O, Ferretti L. A novel USP9Y polymorphism allowing a rapid and unambiguous classification of Bos taurus Y chromosomes into haplogroups. Anim Genet, in press.
• Pala M, Olivieri A, Achilli A, Accetturo M, Metspalu E, Reidla M, Tamm E, Karmin M, Reisberg T, Hooshiar Kashani B, Perego UA, Carossa V, Gandini F, Pereira JB, Soares P, Angerhofer N, Rychkov S, Al-Zahery N, Carelli V, Sanati MH, Houshmand M, Hatina J, Macaulay V, Pereira L, Woodward SR, Davies W, Gamble C, Baird D, Semino O, Villems R, Torroni A, Richards MB. 2012. Mitochondrial DNA signals of late glacial recolonization of Europe from Near Eastern refugia. Am J Hum Genet. 90:915-924.
• Keller A, Graefen A, Ball B, Matzas M, Boisguerin V, Maixner F, Leidinger P, Backes C, Khairat R, Forster M, Stade B, Franke A, Mayer J, Spangler J, McLaughlin S, Shah M 7, Lee C . Harkins TT, Sartori A, Moreno-Estrada A, Henn B, Sikora M, Semino O, Chiaroni J, Rootsi S, Myres NM, Cabrera VM, Underhill PA, Bustamante CD, Vigl EE, Samadelli M, Cipollini G, Haas J, Katus H, O’ Connor BD, Marc Carlson RJ, Meder B, Blin N, Meese E, Pusch CM, Zink A. 2012. New insights into the Tyrolean Iceman’s origin and phenotype as inferred by whole-genome sequencing. Nature Comm 3:698-706.
• Achilli A, Olivieri A, Pala M, Hooshiar Kashani B, Carossa V, Perego UA, Gandini F, Santoro A, Battaglia V, Grugni V, Lancioni H, Sirolla C, Bonfigli AR, Cormio A, Boemi M, Testa I, Semino O, Ceriello A, Spazzafumo L, Gadaleta MN, Marra M, Testa R, Franceschi C, Torroni A. 2011. Mitochondrial DNA backgrounds might modulate diabetes complications rather than T2DM as a whole. PLoS One 6:e21029.
• King RJ, Di Cristofaro J, Kouvatsi A, Triantaphyllidis C, Scheidel W, Myres NM, Lin AA, Eissautier A, Mitchell M, Binder D, Semino O, Novelletto A, Underhill PA, Chiaroni J. 2011. The coming of the Greeks to Provence and Corsica: Y-chromosome models of archaic Greek colonization of the western Mediterranean. BMC Evol Biol 11:69-76.
• Perego UA, Angerhofer N, Pala M, Olivieri A, Lancioni H, Kashani BH, Carossa V, Ekins JE, Gómez-Carballa A, Huber G, Zimmermann B, Corach D, Babudri N, Panara F, Myres NM, Parson W, Semino O, Salas A, Woodward SR, Achilli A, Torroni A. 2010. The initial peopling of the Americas: a growing number of founding mitochondrial genomes from Beringia. Genome Res 20:1174-1179.
• Behar DM, Yunusbayev B, Metspalu M, Metspalu E, Rosset S, Parik J, Rootsi S, Chaubey G, Kutuev I, Yudkovsky G, Khusnutdinova EK, Balanovsky O, Semino O, Pereira L, Comas D, Gurwitz D, Bonne-Tamir B, Parfitt T, Hammer MF, Skorecki K, Villems R. 2010. The genome-wide structure of the Jewish people. Nature 466:238-242.
• Soares P, Achilli A, Semino O, Davies W, Macaulay V, Bandelt HJ, Torroni A, Richards MB. 2010. The archaeogenetics of Europe. Curr Biol. 20:R174-183.
• Chiaroni J, King RJ, Myres NM, Henn BM, Ducourneau A, Mitchell MJ, Boetsch G, Sheikha I, Lin AA, Nik-Ahd M, Ahmad J, Lattanzi F, Herrera RJ, Ibrahim ME, Brody A, Semino O, Kivisild T, Underhill PA. 2010. The emergence of Y-chromosome haplogroup J1e among Arabic-speaking populations. Eur J Hum Genet 18:479-484.
• Pala M, Achilli A, Olivieri A, Hooshiar Kashani B, Perego UA, Sanna D, Metspalu E, Tambets K, Tamm E, Accetturo M, Carossa V, Lancioni H, Panara F, Zimmermann B, Huber G, Al-Zahery N, Brisighelli F, Woodward SR, Francalacci P, Parson W, Salas A, Behar DM, Villems V, Semino O, Bandelt HJ, Torroni A. 2009. Mitochondrial haplogroup U5b3: a far echo of the Epipaleolithic in Italy and the legacy of the early Sardinians. Am J Hum Genet 84:814-821.
• Patin E, Laval G, Barreiro B, Salas A, Semino O, Santachiara-Benerecetti AS, Kidd KK, Kidd JR, Van Der Veen L, Hombert JM, Gessain A, Froment A, Heyer E, Quintana-Murci L. 2009. Origins and population dynamics of African hunter-gatherers and farmers inferred from a multilocus resequencing dataset. PLoS Genetics 5:e1000448.
• Fornarino S, Pala M, Battaglia V, Maranta R, Achilli A, Modiano G, Torroni A, Semino O, Santachiara-Benerecetti SA. 2009. Mitochondrial and Y-chromosome diversity of the Tharus (Nepal): a reservoir of genetic variation. BMC Evol Biol 9:154-159.
No projects are available to students for the current accademic year.