Ugo Cavallaro
Ugo Cavallaro
affiliation: IEO - Istituto Europeo di Oncologia
research area(s): Cancer Biology, Stem Cells And Regenerative Medicine
Course: Molecular Medicine: Molecular Oncology and Computational Biology
University/Istitution: Università di Milano, UNIMI-SEMM
2001. PhD in Experimental Pathology. University of Milano
1993. PhD in Cellular Biology (EMBO guidelines). Dibit, HSR, Milano
1989. Degree in Biological Sciences, summa cum laude.
January 2011 - present. Team Leader at the European Institute of Oncology (IEO), Molecular Medicine Program.

September 2003 - December 2010. Group Leader at IFOM, Milano.

September 2001 - August 2003. Assistant at the University of Basel, Switzerland.

May 1999 - August 2001. Postdoctoral fellow at the Research Institute of Molecular Pathology, Vienna, Austria.
Zecchini S., Bombardelli L., Decio A., Bianchi M., Mazzarol G., Sanguineti, F., Aletti G., Maddaluno L., Berezin V., Bock E., Casadio C., Viale G., Colombo N., Giavazzi R., and Cavallaro U. (2011) The adhesion molecule NCAM promotes ovarian cancer malignancy via FGFR signaling. EMBO Mol Med., in press.

Veggiani G., Ossolengo G., Aliprandi M., Cavallaro U., de Marco A. (2011) Single-domain antibodies that compete with the natural ligand fibroblast growth factor block the internalization of the fibroblast growth factor receptor 1. Biochem. Biophys. Res. Commun., 408:692-696.

Cavallaro U. and Dejana E. (2011) Adhesion molecule signaling: not always a sticky business. Nat. Rev. Mol. Cell Biol., 12:189-197.

Francavilla, C., Berezin V., Bock E., Ami D., de Marco A., Christofori G., and Cavallaro U. (2009). The binding of NCAM to FGFR1 induces a specific cellular response mediated by receptor trafficking. J. Cell Biol., 187:1101-1116.

Maddaluno L., Verbrugge S.E., Martinoli C., Matteoli G., Chiavelli A., Zeng Y., Williams E.D., Rescigno M., and Cavallaro U. (2009) The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells. J. Exp. Med,, 206:623-635.

Francavilla, C. Maddaluno, L. and Cavallaro U. (2009). The functional role of cell adhesion molecules in tumor angiogenesis. Semin. Cancer Biol, 19:298-309

Zecchini S., Bianchi M., Colombo N., Fasani R., Goisis, G., Casadio C., Viale G., Liu J., Herlyn M., Godwin A.K., Nuciforo P., and Cavallaro U. (2008) The differential role of L1 in ovarian carcinoma and normal ovarian surface epithelium. Implications for ovarian carcinoma progression. Cancer Res., 68:1110-1118.

Francavilla C., Loeffler S., Piccini D., Kren A., Christofori G., and Cavallaro U. (2007) Neural cell adhesion molecule regulates the cellular response to fibroblast growth factor. J. Cell Sci., 120: 4388-4394.
No projects are available to students for the current accademic year.